The Cardiology Service (Service) in the Department of Medicine at MSK is seeking applications for a board-certified academic cardiologist to join our Service which is currently staffed by 13 cardiologists and 11 advanced practice providers (APPs) and a cadre of nurses and technologists all devoted to the cardiac care of patients with cancer. This position involves direct inpatient and outpatient cardiac care, echocardiographic and ECG interpretation, and protected time for clinical research. The successful candidate will be an accomplished clinician, with Level II or III training in echocardiography. Special consideration will be given to individuals who have demonstrated strong commitment to scholarly activity. Faculty rank will be determined by the qualifications and experience of the successful candidate. The Cardiology Service at MSK provides consultations for a 500-bed hospital, outpatient clinics, and support for a growing regional network of MSK oncology and affiliated cardiology practices. The service includes a fellowship program that attracts Board Certified cardiologists from the U.S. and abroad for cardio-oncology training. Cardiology is supported by multiple state of the art echocardiography, EKG, stress testing and rhythm monitoring labs at the MSK main campus, other Manhattan sites and at MSK regional locations. Cardiology manages implantable cardiac devises (ICD) for MSK patients. The Service has well established relationships with the country’s leading cardiovascular institutions that are located in NYC and surrounding areas. The ideal candidate should have: - An M.D., M.D./Ph.D., or equivalent with excellent clinical, communication and team skills - Board certification or board-eligible in cardiovascular diseases - Level II competency in Echocardiography (TTE, TEE, stress echo) - Licensure in the state of New York, or eligibility for a medical license in New York is required - A strong interest in pursuing academic excellence with a track record of scholarly achievements - An interest in data analysis and process improvement If you have any questions about this job opportunity, please contact: Xavier Aristy Administrative Assistant aristyx@mskcc.org ** Please include a cover letter, brief statement of prior research experience and research interests, CV, and contact information for three references in your application submission. Base Salary: $150,000-$590,000
The Proteomics Innovation Laboratory at Sloan Kettering Institute (SKI) in New York City is seeking to hire an expert in mass spectrometry-based proteomics. We aim to recruit a dynamic, innovative and motivated Senior Research Scientist to provide state-of-the-art proteomic expertise to innovate and support projects across SKI. The successful candidate will be responsible for designing and executing proteomic experiments, developing LC-MS based proteomics methods and work on cutting-edge approaches (i.e. single cell proteomics, immunopeptidomics, etc). Approaches include, but are not limited to, proteomics, phosphoproteomics, interaction proteomics, targeted proteomics and chemoproteomics. Close collaboration with other scientists to design experiments is required. Expertise in proteomics, data analysis and protein biochemistry, a proven track record in proteomics and knowledge of high-resolution mass spectrometry instruments HPLC systems is preferable. This role provides an opportunity to join a highly dynamic and interdisciplinary team with opportunities to implement innovative research. The Senior Research Scientist will join a state-of-the-art laboratory with comprehensive expertise in mass spectrometry-based proteomics.The ideal candidate should have: • PhD in Chemistry, Biochemistry, Biology or a related field with a minimum of 3 years of research experience in academia and/or industry in proteomics/mass spectrometry • Expertise in mass spectrometry-based proteomics, including proteome profiling, PTM, protein-protein interaction, chemoproteomics, etc. • Experience in targeted proteomics (PRM/SRM) is preferred • Working knowledge of statistics as it applies to experimental design and ability to conduct data analysis using different software (e.g., Perseus, GraphPad Prism, etc.) • Experience with a scripting language (R, Python, etc.) is preferred • Experience with working in an interdisciplinary team of scientists in a highly collaborative environment • Excellent verbal and written communication skills, and the ability to work in a collaborative team environment. Communicate results effectively to a cross-functional team • Demonstrated ability to critically evaluate data and to think creatively about experimental design • Track record of methodological innovation •Record of scientific accomplishments, as indicated by peer-reviewed publications and presentations • Demonstrated ability to contribute to multiple projects in parallel with learning agility and scientific rigor • Strong written/verbal communication skills and ability to collaborate effectively with scientists working in other disciplines Salary: $74,263 – $110,000.
The candidates should be fellowship-trained in interventional radiology and board-eligible in interventional radiology. The candidates should have excellent clinical skills, research experience, and strong interpersonal skills. They must be eligible for medical licensure in New York, board-certified in radiology or be committed to achieving certification in a specified time period, and otherwise qualified for appointment to the MSKCC faculty. The candidate should show superb clinical skills, a patient–centered approach, effective communication skills, research experience, and excellence in teaching. Clinical appointments will be made within MSKCC and academic appointments at Weill Cornell Medical College, commensurate with experience and accomplishments. If you have any questions about this job opportunity, please contact: Dorisela Martinez martind5@mskcc.org Salary: 350,000-500,000 Physician compensation is based on multiple variables. This range represents annual salary only and does not include supplemental performance-based pay or any one-time payments that eligible candidates may be offered at the time of hire.
We are seeking a highly motivated candidate, interested in statistical and computational methods development and application in immuno-oncology studies, for a position as a postdoctoral fellow. This position will focus on analyzing high-dimensional flow cytometry data, single-cell RNA sequencing, multiplex imaging, and spatial transcriptomics in patients treated with immune checkpoint blockade (ICB) with rich clinical annotation. The candidate will have the opportunity to lead the development of novel statistical and computational approaches and work with world’s leading immuno-oncology experts. The ideal candidate should have: - Applicants should hold a Ph.D. degree in biostatistics, statistics, bioinformatics, or a related field, ideally with experience in high dimensional data analysis. - The successful candidate should have solid methodological training in statistics, be comfortable working with large data sets, proficient in at least one of the statistical programming languages R/Matlab/Python.- Have experience working on Unix/Linux systems and basic shell scripting. - Prior experience with single-cell data would be an asset. The successful applicant will be supervised jointly by Drs. Ronglai Shen, Katherine Panageas and Margaret Callahan. If you have any questions about this job opportunity, please contact: Ronglai Shen, PhDshenr@mskcc.org ** Please include a cover letter, brief statement of prior research experience and research interests, CV, and contact information for three references in your application submission. Salary: $55,439 – $100,940
Applications are invited for a position as a Post-Doctoral Fellow to study the mechanisms underlying the pathogenesis of lymphoma involving multi-disciplinary research spanning discovery to biomarker credentialing and translation. The selected candidate for the position will work on one of several research projects including the development of novel strategies for the interrogation of biological complexes, the dissection of deregulated signaling pathways involved in the molecular pathogenesis of cancer, and biomarker discovery. Specific project opportunities also include the interrogation of post-translational modifications that are implicated in cancer pathogenesis and in-vivo studies investigating mechanisms of lymphoma pathogenesis and evolution. The candidate will have opportunities to combine genetic approaches with proteo-genomic analyses to understand lymphoma pathogenesis. Experience and willingness to independently execute experiments in mice is required. Accordingly, the experience with all aspects of immunology, molecular biology and cell biology is desired.The responsibility of the postdoctoral candidate includes working directly with the senior members of the laboratory to design, develop and execute bench experiments and performing data management.The candidate must be able to troubleshoot technical difficulties, maintain adequate records and clearly communicate scientific results and interpretation verbally and in writing to the principal investigator and scientific community. Job Requirements: - The successful candidate must have a Ph.D., M.D. or equivalent doctoral degree. - We are looking for candidates with background and/or strong interest in one or more of the following areas: mouse model of cancer, immunology, and cell biology, computational biology. - Experience and willingness to independently execute experiments in mice is required. - Excellent interpersonal skills to function optimally in the project team and to cooperate with collaborators will be important. Initial appointment will be for 12 months, and depending on performance, opportunity for annual renewals can be extended up to 36 months. Candidate must have 100% research commitment. The position is available immediately, but later starting dates are possible. Salary will be Commensurate with experience and qualifications. Continuation of position is subject to the needs of the department, performance, and availability of funding. If you have any questions about this job opportunity, please contact: Megan S Lim MD, PhD Limm4@mskcc.org
The Department of Pathology at Memorial Sloan Kettering Cancer Center is seeking to recruit a board-certified academic dermatopathologist at the rank of Assistant or Associate Attending level. The Dermatopathology Team, led by Dr. Klaus Busam, is composed of 5 dermatopathologists with extensive expertise in neoplastic and non-neoplastic skin disorders. The position provides an opportunity to practice Dermatopathology in a unique professional environment that emphasizes a multidisciplinary team approach to personalized patient care with cutting edge diagnostic and treatment modalities. Applicants should have a strong interest in collaborative research, for which there are ample opportunities with an outstanding supportive infrastructure. There will be additional opportunity to work and collaborate with digital pathology and machine learning experts on novel technologies and develop AI models as applicable in dermatopathology. Candidates are required to be Board eligible or certified in Anatomic Pathology and Dermatopathology. They will be expected to provide diagnostic services in Dermatopathology, engage in collaborative patient care and translational research efforts with members of our cutaneous oncology disease management teams, and to teach Dermatopathology fellows, students and residents in Pathology and Dermatology. MSK offers a competitive compensation package with exceptional benefits based on experience and accomplishments. Physician compensation is based on multiple variables. For the different appointment levels under consideration, it ranges from $ 222,000 to $ 475,000. This range represents annual salary only and does not include supplemental performance-based pay or any one-time payments that eligible candidates may be offered at the time of hire. If you have any questions about this job opportunity, please contact: Kojo Elenitoba-Johnson, MDChairman, Department of Pathology & Laboratory MedicineMemorial Sloan-Kettering Cancer Center1275 York AvenueNew York, NY 10065Email: ramkisss@mskcc.org
An opening is now available for a postdoctoral researcher in the department of medical physics for individuals interested in combining artificial intelligence in brachytherapy. The two-year project will focus on the development of advanced deep learning and machine learning image processing methods to automatically segment targets on medical images. Opportunities to work on related problems involving natural language processing in patient charts and developing clinical-release software is also possible, time permitting. This is an excellent opportunity for a researcher with a PhD in biomedical engineering, medical physics and computer science who are interested in investigating state-of-the-art artificial intelligence to solve immediate clinical problems, and who want to gain firsthand research and development experience from cancer treatment frontline and to pursue career in technology and healthcare industry in future. The job will involve working with a multi-disciplinary team of computer scientists, medical physicists, and radiation oncologists. The ideal candidate should have: - Strong programming background (Python and Matlab) - Be familiar with deep learning libraries (e.g. Pytorch/Keras) - Knowledge and hands-on experience of machine learning is required. - Prior experience in medical imaging processing or computer vision is highly desirable. - Excellent written and communication skills are required - Successful completion of the project is expected to result in one or more high quality publications. If you have any questions about this job opportunity, please contact: Tonghe Wang, Ph.D. DABR Assistant attending physicist wangt8@mskcc.org ** Please include curriculum vitae in your application submission. Salary: $55,439 - $85,840
Sloan Kettering Institute (SKI) has an exciting opportunity for a Scientific Research Manager (SRM) working with the Computational & Systems Biology and Developmental Biology, as well as SKI Administration. The SRM will coordinate scientific operations, including those of large NIH-funded grants, and help to develop and present the scientific projects and mission. You will:- Work closely with the Chairs of the Computational & Systems Biology and Developmental Biology assigned as well as the Associate Director of SKI Administration- Take responsibility for the communication, networking, and coordination within the assigned programs, and across all of MSK research and clinical programs, as well as Dept of Research Technology Management (RTM) - Lead grant program management within programs, including finding opportunities for peer-reviewed funding, locating suitable applicants, providing support with grant preparation and editing, producing timely submission of proposals, and ensuring timely and accurate follow-up, so as to ensure maximal external research funding- Work with the Associate Director on institute wide projectsYou have:- The position requires a Ph.D. level scientist with broad scientific knowledge, in Life or Medical Sciences, with strong written and verbal skills. Experience in management and program building, preferred. - Background in drug discovery and development, biochemistry, HTS, cell-based assays and animal efficacy studies- Exposure/understanding of medicinal chemistry and/or chemical probes- Strong creativity and ability to talk with scientists and clinicians. Strong motivation to invest in the academic and scientific success of others.- Knowledge of Acrobat Professional Writer, Photoshop, and Illustrator desirableAre you ready to learn more about ourBenefits? $87,300.00-$139,800.00 Please click to learn more about MSK’s compensation philosophy.
We have an opening for hybrid research and imaging physics residency position in the Department of Medical Physics, with a flexible start date for the right candidate. This is a hybrid residency program in which a two-year grant-funded research project is followed by a two-year clinical residency in medical imaging physics. For those who enter the 4-year program without CAMPEP credentials, you will be enrolled in a CAMPEP Certificate program with full tuition support from the department. You will be required to complete the Certificate program during the first two years of the program before entering clinical training. Research for this position will be conducted under Dr. Hao Zhang, PhD, DABR on a project titled “Deep learning enabled fast gated CBCT imaging for lung SBRT.” You will be responsible for algorithm development, experimental validations, and preparation of manuscripts for publication. You will also have the opportunity to participate in the first-in-human clinical trial and translation of this imaging technique to the clinic. The Department of Medical Physics consists of over eighty faculty physicists and computer scientists plus support staff working on various physical problems related to diagnosis and therapy for cancer, in partnership with radiologists, radiation oncologists, and other medical professionals. Medical Physicists in the diagnostic imaging physics track are actively engaged in several research programs that include molecular, MR and CT imaging as well as the new radionuclide therapies called theranostics. Examples include advanced MR acquisition techniques, motion correction, MR fingerprinting, artificial intelligence, and deep learning for image reconstruction in all imaging modalities. MSK is a World leader in imaging and theranostic research and supports one of the largest pre-clinical small animal core facilities in the United States that includes MR, PET, SPECT, CT, ultrasound imaging equipment that provides a conduit for the translation of experimental techniques into clinical trials. Additional highlights include grant-funded research in quantitative MRI, hypoxia imaging, imaging drug delivery, and radionuclide dosimetry. Research and development in radiotherapy physics include the use of artificial intelligence for improved imaging and target localization, real-time tumor tracking, tissue segmentation, treatment planning, and adaptive radiotherapy.Diagnostic, Nuclear and MRI Medical Physicists play a key role in supporting all imaging devices throughout the MSK enterprise, maintaining and harmonizing acquisition protocols, troubleshooting image artifacts, and maintaining equipment accreditation and regulatory compliance. We support well over 500 imaging instruments that include 40 CT scanners, 21 MR scanners, and 17 PET scanners and work with radiologists in the selection of new imaging equipment and the implementation of new imaging techniques. Since diagnostic images are at the core of cancer diagnosis and response assessment, we have a strong philosophy to ensure that all imaging equipment throughout the network is operating at the optimum performance, per the overall mission of MSKCC to advance the state of cancer care. Details of the residency program can be found at https://www.mskcc.org/hcp-education-training/residencies/residency-therapeutic-medical-physics. The successful candidate will be compensated according to the MSKCC standard rates based upon experience. Specifics information on employee benefits offered may be found at https://careers.mskcc.org/learn-about-msk/benefits/. The ideal candidate should have: - Doctorate in medical physics, engineering, or similar scientific discipline.- Expertise on medical imaging and deep learning.- Programing skills with Python and Matlab. - Track record of peer-reviewed publications- Additional requirements may be found on our website (mskcc.or/departments/medical-physics). If you have any questions about this job opportunity, please contact: Christopher J. Watchman, Ph.D., DABR Education Director and Associate Attending Physicist Department of Medical Physics watchmac@mskcc.org** Please include a letter of intent, curriculum vitae & three letters, or reference in your application submission. Salary: $55,439 - $85,402
We have an opening in our combined four-year hybrid residency in Therapeutic Medical Physics in the Department of Medical Physics, available as early as December 2022 with a flexible start date for the right candidate. Our MSKCC CAMPEP Accredited Residency Program in Therapeutic Medical Physics involves two years of dedicated research with the opportunity to obtain a CAMPEP Medical Physics certificate, followed by two years of training in all aspects of clinical radiation therapy. This position may be an excellent opportunity for you to transition your technical skills and apply them to exciting opportunities in cancer medicine. Applicants with CAMPEP degrees are encouraged to apply. Research for this position will be conducted under the direction of Jean Moran, Ph.D. on a project entitled “Applying Machine Learning to Quality Improvement in Radiation Therapy.” The Department of Medical Physics consists of over faculty physicists and computer scientists plus support staff working on various physical problems related to diagnosis and therapy for cancer. MSKCC has an extensive, cutting-edge program in all aspects of radiation oncology physics that seeks to improve the clinical effectiveness of radiation therapy in partnership with radiation oncologists, radiologists, and other medical professionals. Many new programs in radiation therapy research and development are ongoing, including the development of on-board pseudo MRI on a conventional X-ray guided LINAC, real-time motion adaptation during treatment on the MR-linac, the development and clinical use of predictive models using machine learning/AI for treatment planning, improved treatment planning optimization algorithms, integration of MR and PET imaging into radiotherapy decision making and treatment planning, 4D imaging and motion management, the use of Deep Learning and AI for image analysis and tissue segmentation, and the development of informatics-based adaptive radiotherapy processes. Medical physics resources include twenty-nine linear accelerators, one combined treatment room-MRI-Linac system, six HDR units, CT, PET/CT, MRI simulators, and state-of-the-art inter-and intra-fractional imaging and motion management capabilities. We also have access to robust high-performance and GPU computing. We are also partners with the New York Proton Center, which houses one cyclotron, three rotational gantry treatment rooms, one fixed beam treatment room, one research beam room, PET/CT, two CTs, two MRIs, related clinical support space. Details of the residency program can be found at https://www.mskcc.org/hcp-education-training/residencies/residency-therapeutic-medical-physics. The successful candidate will be compensated according to the MSKCC standard rates based upon experience. Specifics information on employee benefits offered may be found at https://careers.mskcc.org/learn-about-msk/benefits/. The ideal candidate should have: - Candidates with strong physics, and/or computer skills and are interested in applying your abilities to medicine. - Candidates with strong deep learning/AI skills are highly preferred. - Doctorate in medical physics, physics, engineering, or a similar scientific discipline.- Additional requirements may be found on our website (mskcc.or/departments/medical-physics). If you have any questions about this job opportunity, please contact: Christopher J. Watchman, Ph.D., DABR Education Director and Associate Attending Physicist Department of Medical Physics watchmac@mskcc.org** Please include a letter of intent, curriculum vitae & three letters, or reference in your application submission. Salary: $55,439 - $85,402
The Myeloma Service in the Department of Medicine at Memorial Sloan Kettering Cancer Center is seeking a full-time faculty member at the Associate Attending level for clinical research for the treatment of patients with myeloma, with a focus in multiple myeloma. The Associate Attending must have experience developing novel therapies for the treatment of patients with multiple myeloma through a wide range of clinical and translational research of novel chimeric antigen receptor (CAR) T cell therapies for multiple myeloma in collaboration with other clinical services and research laboratories.The Associate Attending must have experience publishing research in top tier journals of medicine, oncology, and hematology. Candidates must be board certified or board eligible in medical oncology. Please send your resume/CV to:Saad Z. Usmani, MD, MBA, FACPChief, Myeloma Serviceusmanis@mskcc.org cc: Nicole Britez via britezn@mskcc.org.
Memorial Sloan Kettering Cancer Center (MSK) is one of the world’s premier cancer centers, committed to exceptional patient care, leading-edge research, and superb educational programs. The blending of research with patient care is at the heart of everything we do. The institution is a comprehensive cancer center whose purposes are the treatment and control of cancer, the advancement of biomedical knowledge through laboratory and clinical research, and the training of scientists, physicians and other health care workers. The largest of MSK’s clinical departments, the Department of Medicine (DoM) encompasses experts in solid tumor oncology, hematologic malignancies, subspecialty medicine and supportive and acute care services. Offering a range of services both in multiple sites in New York City and at their suburban outpatient locations in our Regional Care Network (RCN), DoM physicians oversee the care of the whole patient. The RCN serves the areas surrounding Manhattan and extends from Southern New Jersey to Eastern Long Island and brings the same high level of expertise, clinical care, and access to clinical trial protocols that are available at our main campus in New York City. The Genitourinary Oncology Service in the Division of Solid Tumor Oncology, Department of Medicine at Memorial Sloan Kettering Cancer Center is seeking a full-time Clinical Investigator at the Assistant Attending level with a focus on prostate cancer clinical and translational research. Our 34 full time Genitourinary Oncologists see patients with a wide range of malignant diseases including prostate cancer, bladder cancer, kidney cancer, and testicular cancer, among others. The Genitourinary Oncology Service also supports a wide range of clinical and translational research. For this position, candidates should have superb clinical and interpersonal skills and, ideally, experience with clinical research. Candidates must be board certified or board eligible in medical oncology. Service Description: Division of Solid Tumor Oncology Candidates must be board certified or board eligible in medical oncology. Please click on the link to apply; be sure to include a CV, career statement and any additional relevant information. For further faculty recruitment opportunities, please visit MSKCC Faculty Recruitment Portal.
Memorial Sloan Kettering Cancer Center (MSK) is one of the world’s premier cancer centers, committed to exceptional patient care, leading-edge research, and superb educational programs. The blending of research with patient care is at the heart of everything we do. The institution is a comprehensive cancer center whose purposes are the treatment and control of cancer, the advancement of biomedical knowledge through laboratory and clinical research, and the training of scientists, physicians and other health care workers. The largest of MSK’s clinical departments, the Department of Medicine (DoM) encompasses experts in solid tumor oncology, hematologic malignancies, subspecialty medicine and supportive and acute care services. Offering a range of services both in multiple sites in New York City and at their suburban outpatient locations in our Regional Care Network (RCN), DoM physicians oversee the care of the whole patient. The RCN serves the areas surrounding Manhattan and extends from Southern New Jersey to Eastern Long Island and brings the same high level of expertise, clinical care, and access to clinical trial protocols that are available at our main campus in New York City. The Benign Hematology Service in the Division of Hematologic Malignancies is seeking a full-time Clinical Investigator at the Assistant or Associate Attending level. The successful candidate will join the Benign Hematology Service which has a rapidly growing clinical, translational, and bioinformatics-based research programs specifically in the field of cancer-related thrombotic and bleeding disorders. The successful candidate with participate in outpatient and inpatient consultative clinical service and supervise MSKCC clinical fellows. Appointment as Instructor, Assistant, or Associate faculty member at Memorial Sloan Kettering and Weill Cornell Medicine will be commensurate with experience, training, and accomplishments. Service Description: Hematology Service Candidates must be board certified or board eligible in Hematology. Please click on the link to apply; be sure to include a CV, career statement and any additional relevant information. For further faculty recruitment opportunities, please visit MSKCC Faculty Recruitment Portal.
The Sadelain Lab is looking for highly motivated and talentedcandidates to join their team of scientists working on cutting-edge immunotherapy research, focusing on the development of CAR T cells from induced pluripotent stem cells (iPSCs). For more details e-mail Sjoukje van der Stegen (stegens@mskcc.org) and check the website at https://www.mskcc.org/research/ski/labs/michel-sadelain. The ideal candidate should have: - PhD (or impending defense) in T cell biology, T cell development, stem cell biology or cancer immunotherapy - Extensive experience with primary cell culture and multi-parameter flow cytometry - Experience with T cell functional assessment, signal transduction and/or RNA seq analysis are especially valuable - Self-motivated, well-organized and excited to learn - Good interpersonal skills and can work in a team as well as with collaborators Please sendCV, a letter outlining your interest and names/contact information of three references via email to: Sjoukje van der Stegen, PhD Senior Research Scientist stegens@mskcc.org
The Center for Epigenetics Research is seeking a highly motivated and successful individual with a background in epigenetics and molecular biology. As a Senior Research Scientist within the Center for Epigenetics Research (https://www.mskcc.org/research-programs/epigenetics-research), for leading the technology development effort of the Innovation Laboratory. The core mission of this group is to develop new experimental methodologies in epigenetics research and implement these and existing technologies. The group will work in close collaboration with clinicians and scientists at MSK, as well the computational biology and genome analysis group in the Center for Epigenetics research. This position involves the oversight and training of laboratory staff at the M.S. and Ph.D. levels and requires the ability to define and articulate new research directions and experimental approaches. In addition to overseeing day-to-day operations in the laboratory, this role requires a broad base of technical knowledge regarding existing methods in epigenetics research as well as the ability to creatively invent and customize new ones. The senior research scientist will work closely with leadership, experimental and computational biologists, and technical staff in the Center. You will: - Lead and manage laboratory staff- Interview, hire, orient, and train new laboratory staff- Delegate work to staff to meet center goals and requirements- Work with laboratory staff and the director to define and articulate research directions, new techniques, and laboratory procedures for the Innovation Lab- Attend management technique or other leadership classes as referred by supervisor- Evaluate and determine the benchmarking needed and the metrics required for building and monitoring the experimental procedures- As leader of the Innovation Lab, meet with other project leaders to design and execute project enhancements that allow for maximal integration of techniques and staff expertise- Assist in grant writing- Work with Lab Managers and Project Managers to determine the metrics needed to assess quality of and need for updating laboratory procedures- Work with the Computational group to synergize the experimental procedures with the computational analysis- Evaluate the novelty of newly designed methods regarding patentability and potential intellectual property- Ensure data migration occurs in an efficient and timely manner with regard to the needs of core members and collaborators- Aid in the development of the laboratory portion of chargeback for internal and external projects along with other center leadership and director- Implement and optimize commonly used methodologies for epigenetics research to address: gene expression (RNAseq, GRO-seq), histone modifications (ChlP-seq, native ChIP-seq, CUT&RUN, CUT&Tag), chromatin accessibility (ATAC-seq, MNase-seq), DNA methylation (bisulfite-seq, EM-seq), chromatin organization (HiC-techniques), and single cell approaches (SHARE-seq, Paired-tag, …)- Provide consultation and guidance to research scientists and other members of the Center- Guide researchers in choosing the right method for addressing a specific question and train them in sample handling and experimental procedures- Assist collaborators with experimental protocols and development of those The ideal candidate should have: - Doctorate/PhD (at least 3-4 years of experience at Postdoc level)- Extensive hands-on knowledge and experience with the most common high throughput epigenomics profiling techniques such as ChIP-seq, CUT&RUN, ATAC-seq, Bisulfite sequencing and others- Broad experience in molecular biology techniques- Excellent knowledge about epigenetics research- Strong analytical skills- Excellent communication skills, ability to work collaboratively and effectively- Skills in computational biology is a plus- Experience in mentoring and training is a big plus If you have any questions about this job opportunity, please contact: Pierre-Jacques Hamard, Ph.D.Manager, Epigenetics Innovation Research LabHamardP@mskcc.org Salary: $74,263 – $110,000
A postdoctoral position is currently available in an exciting collaboration between Dr.Huangfu (https://www.mskcc.org/research/ski/labs/danwei-huangfu) and Dr. Ziv labs.We are seeking highly motivated individuals with an interest in stem cell and cancerbiology for a project involving the manipulation of human pluripotent stem cells intomodels of neuroendocrine cancer progression. Expertise in developmental biology,organoids, and CRISPR gene editing preferred. If you have any questions about this job opportunity, please contact: Alexa LamoreAdministrative Assistantlamorea@mskcc.org
The Pertsinidis lab in the Structural Biology Program of the Sloan Kettering Institute at MSKCC has immediate openings for Postdoctoral positions. A major focus in our lab is developing cutting-edge single-molecule detection and superresolutionoptical imaging techniques. We further apply the tools we develop to visualize andunderstand some of the most fundamental biological processes that power cellular life. Forexample, our lab has developed modulation interferometry, a single-molecule localization-basedsuper-resolution technique with ~1-2 nm 3D precision and target-locking 3D nanoscopy, atechnique that achieved single-molecule detection in high background, crowded intracellularenvironments. These tools have enabled some of the highest resolution single-molecule studiesto date, providing new biological insights that could not be obtained before (e.g. Wang et al. Cell2016; Li et al., Cell 2019). Successful applicants will become an important member of our vibrant, interdisciplinary team ofphysical and biological scientists. We now develop the next-generation of low-background, noninvasiveand photon-efficient techniques - to further enhance our ability to visualize biologicalprocesses in live cells with single-molecule sensitivity, (sub)-millisecond temporal and (sub)-nanometer 3D spatial resolution. We also further push the limits of extracting high-resolutioninformation from weak signals in optically inhomogeneous, thick, multi-cellular environments,such as tissue explants, 3D organoids and the developing embryo. Finally, we develop newsingle-molecule imaging and machine learning technologies for in situ structuralbiology, to enable for the first time high-resolution structural studies inside cells. Requirements:• Desire to tackle outstanding challenges in optics, microscopy and/or single-moleculebiology• Ph.D. degree in Physics, Chemistry, Optics, Optical Engineering, Biophysics or arelevant scientific or engineering field.• Ability to work effectively in a collaborative, multidisciplinary environment. Experience with single-molecule detection instrumentation and high/super-resolution opticalimaging (e.g. STED/RESOLFT, 4Pi, MINFLUX, SIM, LLS/SPIM approaches, Adaptive Optics,etc.), as well as cryogenic and UHV technologies is preferred but not required. Individuals withadditional working knowledge in areas of biochemistry, molecular, cell and developmentalbiology and/or genetics are strongly encouraged to apply. Please send a CV, names and contactinformation of three references, and a short description of scientific interests to Dr. AlexandrosPertsinidis (PertsinA@mskcc.org).
The Proteomics Core at Sloan Kettering Institute (SKI) is seeking to hire an expert in mass spectrometry-based proteomics. We aim to recruit a dynamic, innovative and motivated Senior Research Assistant to provide state-of-the-art proteomic expertise to support projects across the different programs of SKI. The successful candidate will be responsible for designing and executing proteomic experiments as well as for developing LC-MS based proteomics methods. Approaches include, but are not limited to, proteomics, phosphoproteomics, interaction proteomics, targeted proteomics and chemoproteomics. Close collaboration with scientists to design experiments is required.The Senior Research Assistant will join a state-of-the-art laboratory with comprehensive expertise in mass spectrometry-based proteomics. This position requires bioanalytical expertise, a solid background in proteomics, data analysis and protein biochemistry and knowledge of high resolution mass spectrometry instruments (i.e. Q Exactive, Lumos, Eclipse) and nano HPLC systems. Expertise with TimsTOF and triple quadrupole instruments is preferable, but not required. As Senior Research Assistant you will!• Perform custom proteomic, phosphoproteomic (and other post translational modifications), interaction proteomic, and targeted proteomic experiments• Independently develop, optimize, and validate new LC/MS methods• Use, maintain, and troubleshoot high resolution mass spectrometers (Thermo Q Exactive Plus, Lumos, Eclipse) and nano LC instruments. Similar experience with the Bruker TimsTOF instruments is preferred, but not required• Independently conceptualize, design, and conduct proteomic experiments (including experimental design and basic data collection)• Apply open source and vendor-developed software for data analysis (e.g., Max Quant, Proteome Discoverer, Spectronaut, etc.)• Ensure that all research/discovery work is conducted with highest quality and ethical guidelines and in accordance with relevant regulatory, QC, and compliance guidelines• Maintain laboratory records and adherence to safety policies• Be responsible for monitoring and updating costumer’s requests in iLAB• Be responsible for monitoring the inventory for the laboratory. Oversee generation of purchase orders for supplies and equipment• Communicate with vendor technical support and sales representatives as necessary• Train and supervise technicians You have:• A Bachelor’s Degree in a Biological, Chemistry, or Science related field with at least 6 years of relevant full-time experience or a Master’s degree with 3 years full-time relevant experience• Expertise in mass spectrometry-based proteomics, including proteome profiling, PTM, protein-protein interaction, chemoproteomics, etc.• Work independently as well as with an interdisciplinary team of scientists in a highly collaborative environment• Excellent verbal and written communication skills, and the ability to work in a collaborative team environment $27.34-$42.36 hourly Please click to learn more about MSK’s compensation philosophy.
The Xavier Lab is seeking a Postdoctoral Research Scholar to join our Computational Systems and Biology program at Memorial Sloan Kettering. The ideal candidate has a track record of computation and experiment in systems biology. We will consider experimentalists who want to gain computational skills and computational biologists who want to gain experimental skills. The Xavier lab is collaborative: Our team members are trained in diverse areas such as physics, cancer biology, and microbiology. Recent interests include metabolic rewiring in cancer cells, the interaction between gut microbes and colorectal cancer and the ecology of the gut microbiome. We collaborate with physician-scientists to explore the clinical translation of our basic science.At the Computational and Systems Biology program, we offer competitive salaries above the MSK table (see https://www.mskcc.org/education-training/postdoctoral/resources-postdocs/compensation-benefits-resources). The Xavier lab has an excellent track record of training postdocs for their careers of choice in academics and industry (see https://xavierlab.org/people/). MSK offers outstanding resources for the advancement of postdocs, including guidance in grant writing and job searching.For more details e-mail Joao Xavier at xavierj@mskcc.org and check our webpage at https://www.mskcc.org/research/ski/labs/joao-xavier. The ideal candidate should have: - A PhD (or an upcoming defense) in biological sciences or a related field such as biophysics, bioengineering, systems biology, and microbiology.- A track record of peer reviewed publications.- An interest in combining experimental and computational biology to develop an exciting, independent research project in the broad field of systems biology. If you have any questions about this job opportunity, please contact: Contact Person: Joao XavierContact Email:xavierj@mskcc.org Salary: $55,439 – $100,940
We are seeking a Postdoctoral Associate to work within the shared lab of HHMI Investigator Dr. Tobias Walther and his scientific partner Dr. Robert Farese at Sloan Kettering Institute/Memorial Sloan Kettering Cancer Center in New York City.The Farese & Walther Laboratory studies the mechanisms of lipid metabolism, storage and homeostasis. The lab uncovers the biochemical, physical and cell biological principles that cells use to store lipids and to determine how lipid balance and storage are maintained. The lab also studies how processes of lipid storage affect physiology and disease. For our joint laboratory, we seek an outstanding individual with Ph.D. training in biochemistry, structural biology, cell biology or physiology to study the mechanistic basis of lipid storage in lipid droplets or lipid metabolism in neurodegenerative diseases and cancer. General Qualifications:- PhD. and/or M.D./Ph.D. degree in cell biology, biochemistry, structural biology, or molecular biology- Effective communication skills, self-motivated, and a strong work ethic- Ability to work both independently and in a collaborative group environment- Strong publication record is highly preferredIf you have any questions about this job opportunity, please contact: Eileen Ortizortize5@mskcc.org Salary: $55,439 – 100,940
