Managing Director, MSK Ventures

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Pioneering Impact: Managing Director, MSK Ventures

About Us
At Memorial Sloan Kettering (MSK), we are united by a singular purpose: revolutionizing oncology care and turning groundbreaking science into life-changing solutions. MSK Ventures is created with the intent that it is the forum where innovation meets impact. By investing in transformative early-stage companies that harness MSK's cutting-edge technologies, we bridge the gap between research and  first-in-class and best-in-class medicines that address unmet medical need.

Join us in shaping the future of oncology care—aligning bold science with strategic vision to end cancer for life.

Role Overview
The Managing Director, MSK Ventures, will lead MSK’s venture capital initiatives, spearheading investments in oncology-focused startups poised to transform cancer care. Reporting to the Chief Strategy Officer, this role demands entrepreneurial vision, strategic expertise, and a passion for both creating and driving meaningful impact.

This is a rare opportunity to collaborate with world-class scientists, lead transformative investments, and expand MSK Ventures’ influence in the biotech and healthcare ecosystems—all while advancing MSK’s mission to end cancer for life.

Key Responsibilities

Strategic Investment Leadership

• Develop and execute investment theses focused on oncology innovation.
• Source, evaluate, and negotiate early-stage investment opportunities with transformative potential.
• Lead due diligence, financial modeling, and market analyses to assess opportunities.Oversee portfolio strategy, fund operations, and risk management to optimize financial returns.

Entrepreneurial and Portfolio Support

• Mentor startup leaders on operational scaling, fundraising, business development and navigating complex regulatory landscapes.
• Provide strategic guidance to portfolio companies, fostering alignment with MSK’s mission.
• Broker connections between startup leaders and key opinion leaders

• Monitor portfolio performance and liquidity events, delivering actionable insights to MSK leadership.

Ecosystem Engagement

• Position MSK Ventures as a leader in oncology-focused venture capital.
• Build strategic relationships with venture capitalists, accelerators, and healthcare innovators.
• Act as a champion for MSK’s mission in external partnerships and startup communities.
• Can represent MSK Ventures as a thought leader at conferences and other public forums 

Board and Stakeholder Communication

• Serve as the primary liaison to MSK’s Board of Trustees, delivering detailed investment reports and strategic updates.
• As appropriate, secure board representation on behalf of MSK in portfolio companies and provide strategic guidance and oversight
• Collaborate with MSK scientists, the Office of Technology Development, and external stakeholders to align goals and outcomes.

Inspirational Leadership

• Inspire trust and alignment across all levels of MSK, from scientific teams to executive leadership.
• Foster a culture of innovation, accountability, and mission-driven impact.

Key Qualifications and Core Skills

• Strategic Visionary: Proven leadership in early-stage venture capital, seed investing, or startup growth, with a record of scaling transformative opportunities.
• Oncology and Healthcare Expertise: Deep understanding of oncology, life sciences, and healthcare regulations, with the ability to translate innovation into measurable outcomes.
• Dealmaker: Demonstrated ability to catalyze, drive and close business development partnerships, financing and exit opportunities
• Financial Acumen: Expertise in investment analysis, capital formation, portfolio risk management, and strategic financial decision-making.
• Entrepreneurial Spirit: A natural innovator with a passion for startups and scaling groundbreaking ideas.
• Collaborative Leader: Demonstrated success building trust across diverse teams and stakeholders, fostering alignment and shared purpose.
• Mission-Driven Mindset: Commitment to MSK’s mission to end cancer for life, blending scientific curiosity with strategic impact.

Additional Information

• Location: This is a hybrid role based in New York City, with the expectation to be onsite for stakeholder meetings and collaboration. We are open to candidates willing to relocate.
• Pay Range: $400-450k base salary with a competitive and compelling bonus structure

Helpful Links:

• MSK Compensation Philosophy
• Review Our Comprehensive Benefit Offerings

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MSK is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision.  

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